Área de Farmacología

Acceso al grupo de investigación FARMACOLOGÍA (FARMA01) en el portal científico de la Universidad de León.

Principales publicaciones

• Occurrence and risk assessment of organochlorine pesticide residues in tea and herbal products in Spain

  Diez R, Lopez C, Rodriguez JM, de la Puente R, Romero B, Vazquez EM, Diez MJ, Fernandez N, Sahagun AM. 
  Frontiers in Sustainable Food Systems, 9:1575428(2025). doi:10.3389/fsufs.2025.1575428

• Pharmacokinetic of meloxicam in different animal species: A comprehensive review

  de la Puente, Diez R, Diez MJ, Fernandez N, Sahagun AM, Rodriguez JM, García JJ, Lopez C. 
  Veterinary Sciences, 11:519(2024). doi:10.3390/vetsci11110519

• Pharmacokinetic pattern of menbutone in calves after single intravenous and intramuscular administration

  Diez R, Rodriguez JM, Lopez C, de la Puente R, Sierra M, Diez MJ, Fernandez N, García JJ, Sahagun AM. 
  Animals, 14:2540(2024). doi:10.3390/ani14172540

• Drug prescription pattern in exotic pet and wildlike animal practice: A retrospective study in a Spanish veterinary teaching hospital from 2018 to 2022

  Romero B, Susperregui J, Sahagun AM, Fernandez N, Lopez C, de la Puente R, Altonaga J, Diez R.
  Frontiers in Veterinary Science, 10(2024). doi:10.3389/fvets.2023.1328698.

• Tribulus terrestris and sport performance: A quantitative and qualitative evaluation of its advertisement and availability via online shopping in six different countries

  Garcia JF, Seco-Calvo J, Arribalzaga S, Diez R, Lopez C, Fernandez N, Garcia JJ, Diez MJ, de la Puente R, Sierra M, Sahagun AM.  
  Nutrients, 16:9(2024). doi:10.3390/nu16091320.

• Face-to-face and online teaching experience on experimental animals and alternative methods with Nursing students: A research study

  Garcia JF, Fernandez N, Lopez C, Diez R, Rodriguez JM, Sahagun AM.  
  BMC Nursing, 22:105(2023). doi:10.1186/s12912-023-01172-5.

• Use of medicinal plants by veterinary practitioners in Spain: A cross-sectional survey

  Romero B, Susperregui J, Sahagun AM, Diez MJ, Fernandez N, Garcia JJ,  Lopez C, Sierra M, Diez R.  
  Frontiers in Veterinary Science, 9:1060738(2022). doi:10.3389/fvets.2022.1060738.

• Development and validation of a sensitive HPLC assay for determination of sparfloxacin according to the European Medicines Agency Guideline

  Lopez C, Diez R, Rodriguez JM, Sierra M, Garcia JJ, Fernandez N,  Diez MJ,  Sahagun AM
  Separations, 9:223(2022). doi:10.3390/separations9080223.

• Herbs as an active ingredient in sport: Availability and information on the internet

  Garcia JF, Arrizabalaga S, Diez R, Lopez C, Fernandez N, Garcia JJ,  Diez MJ, Seco-Calvo J, Sierra M, Sahagun AM
  Nutrients, 14:2764(2022). doi:10.3390/nu14132764.

• Potentially inappropriate medication and polypharmacy in Nursing Home residents: A cross-sectional study

  Diez R, Cadenas R, Susperregui J, Sahagun AM, Fernandez N, Garcia JJ,  Sierra M, Lopez C
  Journal of Clinical Medicine, 11:3808(2022). doi:10.3390/jcm11133808.

• Drug-related problems and polypharmacy in Nursing Home residents: A cross-sectional study.

  Diez R, Cadenas R, Susperregui J, Sahagun AM, Fernandez N, Garcia JJ,  Sierra M, Lopez C
  International Journal of Environmental Research and Public Health, 19:7(2022). doi:10.3390/ijerph19074313.

• Determination of menbutone: Development and validation of a sensitive HPLC assay according to the European Medicines Agency Guideline.

  Lopez C, Diez R, Rodriguez JM, Sierra M, Garcia JJ,  Fernandez N, Diez MJ, Sahagun AM
  Separations, 9:84(2022). doi:10.3390/separations9040084.

• Improvement of albendazole bioavailability with menbutone administration in sheep.

  Diez R, Diez MJ, Garcia JJ, Rodriguez JM, Lopez C, Fernandez N, Sierra M, Sahagun AM
  Animals, 12:463(2022). doi:10.3390/ani12040463.

• Availability of antibiotics for veterinary use on the internet: A cross-sectional study.

  Garcia JF, Diez MJ, Sahagun AM, Diez R, Sierra M, Garcia JJ, Lopez C, Fernandez N
  Frontiers in Veterinary Science, 8:798850(2022). doi:10.3389/fvets.2021.798850.

• Distribution of flumequine in intestinal contents and colon tissue in pigs after Its therapeutic use in the drinking water.

  Rodriguez JM, Diez MJ, Sierra M, Garcia JJ, Fernandez N, Diez R, Sahagun AM
  Animals, 11:1514(2021). doi:10.3390/ani11061514.

• Prevalence and associated factors of polypharmacy in nursing home residents: A cross-sectional study.

  Cadenas R, Diez MJ, Fernandez N, Garcia JJ, Sierra M, Lopez C, Susperregui J, Diez R
  International Journal of Environmental Research and Public Health, 18:2037(2021). doi:10.3390/ijerph18042037.

• The online sale of antibiotics for veterinary use.

  García JF, Diez MJ, Sahagún AM, Diez R, Sierra M, Garcia JJ, Fernandez N
  Animals, 10:3(2020). doi:10.3390/ani10030503.

• Study of master formulas for animal use in a pharmacy in an experimental animal model.

  García V, Díez R, Sahagún AM, Susperregui J, Fernández MN, García JJ, Sierra M, Diez MJ
  Journal of Veterinary and Animal Research, 2:104(2019). doi:10.1186/s12906-017-1809-x.

• Assessment of the antioxidant/hypolipidemic relationship of Sideritis hyssopifolia in an experimental animal model.

  Coto E, Fernandez N, Garcia JJ, Diez MJ, Sahagun AM, Sierra M.
  Molecules, 24:2049 (2019). doi:10.1186/s12906-017-1809-x.

• Influence of Plantago ovata husk (dietary fiber) on the bioavailability and other pharmacokinetic parameters of metformin in diabetic rabbits.

  Díez R, García JJ,Diez MJ, Sahagun AM, Sierra M, Fernández N.
  BMC Complementary and Alternative Medicine, 17:298 (2017). doi:10.1186/s12906-017-1809-x.

• Evaluation of the association metformin: Plantago ovata husk in diabetic rabbits.

  Díez-Láiz R, García-Vieitez JJ,Diez-Liébana MJ, Sierra-Vega M, Sahagún-Prieto AM, Calle-Pardo AP, Fernández-Martínez N.
  Journal of Diabetes Research, 2015:167526. (2015). doi:10.1155/2015/167526.

• Study of the protective effect on intestinal mucosa of the hydrosoluble fiber Plantago ovata husk.

  Sahagún AM, Vaquera J, García JJ, Calle ÁP, Diez MJ, Fernandez N, Loro JF, Portilla HO, Sierra M.
  BMC Complementary and Alternative Medicine, 15:298. (2015). doi:10.1186/s12906-015-0827-9.

• Systemic and mammary gland disposition of enrofloxacin in healthy sheep following intramammary administration.

  López C, García JJ, Sierra M, Diez MJ, Pérez C, Sahagún AM, Fernandez N.
  BMC Veterinary Research, 11:88. (2015). doi:10.1186/s12917-015-0406-9.

• A randomised clinical trial to evaluate the effects of Plantago ovata husk in Parkinson patients: changes in levodopa pharmacokinetics and biochemical parameters.

  Fernandez-Martinez MN, Hernandez-Echevarria L, Sierra-Vega M, Diez-Liebana MJ, Calle-Pardo A, Carriedo-Ule D, Sahagún-Prieto AM, Anguera-Vila A, Garcia-Vieitez JJ.
  BMC Complementary and Alternative Medicine, 14:296. (2014). doi:10.1186/1472-6882-14-296.

• Enrofloxacin: pharmacokinetics and metabolism in domestic animal species.

  López-Cadenas C, Sierra-Vega M, García-Vieitez JJ, Diez-Liébana MJ, Sahagún-Prieto AM, Fernández-Martínez N.
  Current Drug Metabolism, 14 (10), 1042-58. (2013).

• Hypoglycemic and hypolipidemic potential of a high fiber diet in healthy versus diabetic rabbits.

  Díez R, García JJ, Diez MJ, Sierra M, Sahagún AM, Calle ÁP, Fernández N.
  BioMed Research International, 960568. (2013). doi: 10.1155/2013/960568.

• Tissue distribution of enrofloxacin after intramammary or simulated systemic administration in isolated perfused sheep udders.

  López Cadenas C, Fernández Martínez N, Sierra Vega M, Diez Liébana MJ, Gonzalo Orden JM, Sahagún Prieto AM, García Vieitez JJ.
  American Journal of Veterinary Research, 73 (11), 1728-34. (2012).

• Pharmacokinetic behavior of doxycycline after intramuscular injection in sheep.

  Castro Robles LJ, Sahagún Prieto AM, Diez Liébana MJ, Fernández Martínez N, Sierra Vega M, García Vieitez JJ.
  American Journal of Veterinary Research, 73 (5), 714-8. (2012).

• Drug interactions with the dietary fiber Plantago ovata husk.

  Fernandez N, Lopez C, Díez R, Garcia JJ, Diez MJ, Sahagun A, Sierra M.
  Expert Opinion in Drug Metabolism & Toxicology, 8 (11), 1377-86. (2012).